eng Science and Education Publishing Journal of Food and Nutrition Research 2333-1240 2019-03-13 7 3 213 223 10.12691/jfnr-7-3-6 JFNR2019736 article Snigdha Misra snigdha_misra@imu.edu.my 1 Debapriya Mohanty 2 Swati Mohapatra 3 Division of Nutrition and Dietetics, School of Health Sciences, International Medical University, 57000, Kuala Lumpur, Malaysia Research Associate, Institute of Life Sciences, 751023 Bhubaneswar, Odisha, India Department of Biotechnology, Amity University (AIMT), Noida 201313, Uttar Pradesh, India Probiotics are live microbes which serve as excellent functional food ingredients, to improve human health. They provide essential metabolites with dietary and therapeutic characteristics which confers numerous health benefits. They ensure a proper maintenance of the gut health through complex interactions across the gut-brain axis. The probiotics enter into the body through food. Probiotics can exist naturally or be infused in food. Food products containing probiotics are viable modes for a healthy gut. Understanding the mechanism of action of the probiotic strains and their interaction with the gut microflora is absolutely necessary. This review elaborates on the applications of probiotics in food .It also describes the possible mechanism of action and its clinical significance. http://pubs.sciepub.com/jfnr/7/3/6/jfnr-7-3-6.pdf probiotics food formulations gastroenteritis clinical implications