@article{jfnr2019731,
author={{Kang, Hyun Woo and Kwak, Sang Jae},
title={Regulatory Activities from Conjugated Linoleic Acid of p38 Protein in Melanoma Cells},
journal={Journal of Food and Nutrition Research},
volume={7},
number={3},
pages={183--186},
year={2019},
url={http://pubs.sciepub.com/jfnr/7/3/1},
issn={2333-1240},
abstract={This study investigated the activities of <i>trans</i>10,<i>cis</i>12-conjugated linoleic acid (CLA) were then passed through the p38 in <i>in vitro</i> model. Cell viability, apoptosis, expression of p38 was evaluated using B16 melanoma cells. Our result showed that the <i>trans</i>10,<i>cis</i>12-CLA increased cell apoptosis in melanoma cells. In addition, CLA stimulated the expression of p38 and phosphorylation p38 (p-p38) level using western blotting. The p38 was presumed that the CLA were involved in regulation of apoptosis-related pathway in the melanoma cells signaling pathway. Considering the results obtained, the present study finding that the regulatory activities of <i>trans</i>10,<i>cis</i>12-CLA may be important as a therapeutic target in ameliorating melanoma cells mediated cancer or/and tumor on <i>in vitro</i> model.},
doi={10.12691/jfnr-7-3-1}
publisher={Science and Education Publishing}
}