@article{jfnr2019722,
author={{O., Ibrahim H. and O., Osilesi and O., Adebawo O. and D., Onajobi F. and B., Muhammad L. and O., Karigidi K.},
title={<i>In vitro</i> Assessment of the Potential Antioxidant and Antidiabetic Properties of Edible Parts of <i>Chrysophyllum </i><i>albidum</i> Fruit Extracts},
journal={Journal of Food and Nutrition Research},
volume={7},
number={2},
pages={105--113},
year={2019},
url={http://pubs.sciepub.com/jfnr/7/2/2},
issn={2333-1240},
abstract={<i>Chrysophyllum albidum </i>(Linn)<i> </i>belongs to Sapotaceae family and commonly called African star apple. It is traditionally used for the treatment of various ailments. This study aimed at investigating <i>in vitro </i>antidiabetic and antioxidant properties of three edible parts of <i>Chrysophyllum albidum </i>fruit extracts. Lyophilized <i>C. albidum </i>fruit pulp, skin and seed shell pericarp powders were extracted using aqueous and methanol as solvents. <i>In vitro </i>antioxidant (2,2-diphenyl-1-picrylhydrazyl: DPPH, Ferrous Ion chelating, Antilipid peroxidation, Hydroxyl radical and Hydrogen peroxide scavenging assay as well as estimation of total phenolic, flavonoid and antioxidant contents) assay and antidiabetic (¦Á-amylase and ¦Á<i>-</i>glucosidase inhibitory assay) activities of extracts were evaluated. The study revealed that methanol skin extract of <i>C. albidum </i>fruit contained the highest levels of total phenolics (19.0 ¡À 0.16mg GAE/g dry weight), flavonoids (41.27 ¡À mgQE/g dry weight) and antioxidant (98.51 ¡À 0.10mg AAE/g dry weight) and exhibited comparable scavenging property with standards using DPPH, deoxyribose and hydrogen peroxide as substrates. Significant ¦Á-amylase (86.45 ¡À 0.97) and ¦Á-glucosidase (85.07 ¡À 0.71) inhibitory activities were also observed in methanol skin extract of <i>C. albidum </i>fruit, which was comparable with acarbose standard drug -99.04 ¡À 0.04 and 98.99 ¡À 0.05 respectively. Results demonstrate the antidiabetic and antioxidant potential of methanol skin extract of <i>C. albidum </i>fruit and indicate that <i>C. albidum</i> fruit skin could have therapeutic value in diabetes and the related condition of oxidative stress. Hence, further study by <i>in vivo</i> model would be required for the plant¡¯s potential in the management and/or prevention of diabetes.},
doi={10.12691/jfnr-7-2-2}
publisher={Science and Education Publishing}
}