@article{jfnr2017568,
author={{Jeong, Heesun and Kim, Ok-Kyung and Park, Jeongjin and Kim, Kyungmi and Chung, Jin Woong and Shim, Sangin and You, Yanghee and Jun, Woojin},
title={Ethanol Extract of <i>Eriobotrya japonica</i> Leaves Enhanced Swimming Capacity in Mice},
journal={Journal of Food and Nutrition Research},
volume={5},
number={6},
pages={413--417},
year={2017},
url={http://pubs.sciepub.com/jfnr/5/6/8},
issn={2333-1240},
abstract={<i>Eriobotrya japonica</i> is known as ¡®Loquat¡¯ and cultivated in Korea, China, Japan, and India. The present study aims to investigate the effect of <i>Eriobotrya japonica</i> leaves ethanol extract (EJLE) on swimming capacity in mice. Mice were administered distilled water (EX-CON) or 1 g kg<SUP>-1</SUP> per day of EJLE (EX-EJLE) for 14 days. Exhaustive swimming time was significantly prolonged (by 1.4-fold) in EX-EJLE group compared to that in EX-CON group (<i>P </i>&lt; 0.05). EX-EJLE group showed high nonesterified fatty acid (NEFA) and glycogen levels during swimming (<i>P </i>&lt; 0.05). When compared to EX-CON, the EX-EJLE exhibited significant increases in antioxidant enzymes activities including catalase (CAT), superoxide dismutase (SOD), and glutathione peroxidase (GPx) and glutathione (GSH) level as well as and decrease in malondialdehyde (MDA) level (<i>P </i>&lt; 0.05). EJLE elevated the mRNA expression of carnitine palmitoyltransferase-1, ¦Â-hydroxyacyl coenzymes dehydrogenase, peroxisomal proliferator activated receptors-¦Ä, and uncoupling protein-3 in muscle (<i>P </i>&lt; 0.05). These results suggest that EJLE supplementation could improve swimming capacity by ameliorate the physical exhaustion through enhancing utilization of fatty acid, facilitating lipid catabolism, and elevating antioxidant capability.},
doi={10.12691/jfnr-5-6-8}
publisher={Science and Education Publishing}
}