@article{jfnr2016472,
author={{Bamigboye, Comfort Olukemi and Oloke, Julius Kola and Dames, Joanna Felicity},
title={Biological Activity of Extracellular and Intracellular Polysaccharides from <i>Pleurotus tuber-regium </i>Hybrid and Mutant Strains},
journal={Journal of Food and Nutrition Research},
volume={4},
number={7},
pages={422--428},
year={2016},
url={http://pubs.sciepub.com/jfnr/4/7/2},
issn={2333-1240},
abstract={<i>Pleurotus</i><i> tuber-regium </i>(Fr.) Singer (1951) is a unique sclerotium-forming edible and medicinal mushroom. Interestingly, both the sclerotium and mushroom are edible and are often used for curing various ailments. Previous studies have focused on the antimicrobial and antioxidant activity of the extracellular polysaccharide (EPS) from wild <i>P. tuber-regium</i>. There has been no report on the intracellular polysaccharide (IPS) of the wild mycelia, likewise there is very meager information on the improvement of the perceived potentials of <i>P. tuber-regium</i>. This research study analysed the EPS and IPS fractions of <i>P. tuber-regium</i> hybrid and mutant strains. The antimicrobial potential of the IPS and EPS fractions, their scavenging activity on 1, 1-diphenyl¨C2picryhydrazyl (DPPH) and Hydroxyl radicals were also determined. Both IPS and EPS fractions of <i>P. tuber-regium</i> hybrids and mutants showed increased DPPH and hydroxyl scavenging activity over the wild<i> P. tuber-regium </i>with an EC<SUB>50</SUB> mostly &lt; 1 mg/ml. The antimicrobial activity of the IPS from a mutant strain had an IC<SUB>50</SUB> of 15.6 mg/ml compared to the wild type (18.75 mg /ml). This study showed that selected mutant and hybrids of <i>P. tuber-regium</i> had increased radical scavenging activity indicating potentially increased biological activity that could offer increased benefit as a neutraceutical.},
doi={10.12691/jfnr-4-7-2}
publisher={Science and Education Publishing}
}