Science and Education Publishing Journal of Food and Nutrition Research 2333-1240 4 4 2016 5 4 Relationship between Inflammation and Handgrip Strength among Non-critical Inpatients 201 204 EN Zhiwen Ge Zhongxin Hong Department of Nutrition, Beijing Friendship Hospital, Capital Medical University, Beijing 100050, China Jia Wang Bingjie Ding Lihong Zhang Wei Li Yanxia Bi Zhongyi Gu Weihua Qu Li Wu JFNR2016441 10.12691/jfnr-4-4-1 2015 11 24 2016 4 5 2016 5 2 Purpose: To analyze the relationship between inflammation and handgrip strength (HGS), an indicator of nutritional status, in inpatients with non-critical illnesses. Materials and Methods: HGS was measured in 530 inpatients (mean age = 56.4 ± 15.2 years) with a handgrip dynamometer. Nutrition risk was evaluated by administration of the nutrition risk screening-2002 tool. High-sensitivity C reactive protein (hs-CRP) measurements were made with an immuno-turbidimetric assay. Linear regression was used to assess relationships between variables. T-tests, Mann-Whitney U tests, and Kruskal-Wallis H tests were used to detect significant differences. Results: After accounting for gender, age, and nutrition risk, hs-CRP level was a significant predictor of HGS (β-coefficient = -0.1, p < 0.05). Conclusion: HGS was associated inversely with inflammation in hospitalized patients with non-critical illnesses. This finding suggests that relieving inflammation may benefit HGS, which could potentially lead to improved outcomes in terms of relief of inflammation, shorter hospital stays, decreased re-hospitalization rates, and decreased mortality rates.