eng Science and Education Publishing Journal of Food and Nutrition Research 2333-1240 2016-05-04 4 4 201 204 10.12691/jfnr-4-4-1 JFNR2016441 article Zhiwen Ge 1 Zhongxin Hong hongzhongxin@vip.sina.com 1 Jia Wang 1 Bingjie Ding 1 Lihong Zhang 1 Wei Li 1 Yanxia Bi 1 Zhongyi Gu 1 Weihua Qu 1 Li Wu 1 Department of Nutrition, Beijing Friendship Hospital, Capital Medical University, Beijing 100050, China Purpose: To analyze the relationship between inflammation and handgrip strength (HGS), an indicator of nutritional status, in inpatients with non-critical illnesses. Materials and Methods: HGS was measured in 530 inpatients (mean age = 56.4 ± 15.2 years) with a handgrip dynamometer. Nutrition risk was evaluated by administration of the nutrition risk screening-2002 tool. High-sensitivity C reactive protein (hs-CRP) measurements were made with an immuno-turbidimetric assay. Linear regression was used to assess relationships between variables. T-tests, Mann-Whitney U tests, and Kruskal-Wallis H tests were used to detect significant differences. Results: After accounting for gender, age, and nutrition risk, hs-CRP level was a significant predictor of HGS (β-coefficient = -0.1, p < 0.05). Conclusion: HGS was associated inversely with inflammation in hospitalized patients with non-critical illnesses. This finding suggests that relieving inflammation may benefit HGS, which could potentially lead to improved outcomes in terms of relief of inflammation, shorter hospital stays, decreased re-hospitalization rates, and decreased mortality rates. http://pubs.sciepub.com/jfnr/4/4/1/jfnr-4-4-1.pdf HGS inflammation high-sensitivity-c reactive protein inpatients non-critical illness