Science and Education Publishing Journal of Food and Nutrition Research 2333-1240 4 11 2016 11 17 Antioxidant Activity and Phytochemical Composition of Solanum corymbiflorum Fractions (Leaves and Fruits) 736 741 EN Mariana Piana Post-Graduate Program in Pharmaceutical Sciences, Universidade Federal de Santa Maria, Santa Maria, Brazil Roberta da silva Jesus Aline Augusti Boligon Sílvio Terra Stefanello Thiele Faccim de Brum Camilla Filippi dos Santos Alves Natalia Jank Mossmann Bianca Vargas Belke Félix Alexandre Antunes Soares Sara Marchesan de Oliveira Liliane de Freitas Bauermann JFNR20164116 10.12691/jfnr-4-11-6 2016 6 16 2016 9 29 2016 11 15 The antioxidant activity and phenolic compounds of the chloroform (CHCl3), ethyl acetate (AcOEt) and n-butanol (n-BuOH) fractions from Solanum corymbiflorum leaves and fruits were evaluated. The AcOEt fraction of the leaves presented the highest content of total polyphenols (114.00 mg GAE/g) and the best antioxidant capacity by 1,1-diphenyl-2-picrylhydrazyl (DPPH) test (IC50 = 31.90 µg/mL). For the fruits, the same fraction exhibited the highest content of phenolics (99.77 mg GAE/g) and best results in the DPPH test (IC50 = 141.47 µg/mL). In relation to 2',7'-dichlorofluorescein diacetate (DCFH-DA) and thiobarbituric acid reactive substances (TBARS) assays, the CHCl3 fraction of leaves and fruits showed better results than the other samples analyzed. Besides of the phenolic compounds, the alkaloids contributed in the activity. Rutin, chlorogenic and caffeic acids quantified by HPLC are some of phenolic compounds responsible by this activity S. corymbiflorum can be a promising source of natural antioxidants. However, more in vivo studies are required to stimulate the consumption and its other potentialities.