@article{jfnr2015359,
author={{Ke, Zunli and pan, Yu and Xu, Xiaodan and Nie, Chao and Zhou, Zhiqin},
title={<i>Citrus</i> Flavonoids and Human Cancers},
journal={Journal of Food and Nutrition Research},
volume={3},
number={5},
pages={341--351},
year={2015},
url={http://pubs.sciepub.com/jfnr/3/5/9},
issn={2333-1240},
abstract={Nowadays cancers pose a great threat to the health of human beings. Based on studies on the flavonoids and other bioactive compounds of <i>Citrus</i> fruits in current literature, it was widely suggested that the consumption of <i>Citrus</i> fruits is beneficial to the prevention and treatment of human chronic diseases including cancers. In the past decades, the study concerning <i>Citrus</i> flavonoids has covered various areas including the type, content and distribution of flavonoids in fruits; their variation between wild and cultivated genotypes; their antioxidant, anti-inflammation, anti-aging, antimicrobial and anticarcinogenic activities. To enlighten future <i>Citrus</i> germplasm study, this review introduces briefly the functions of main types of <i>Citrus</i> flavonoids, including antioxidant, anti-inflammation and anti-aging activities, and their relationships to human cancers. Most importantly, the mechanisms of action by which <i>Citrus</i> flavonoids play their roles in human cancer prevention and treatment were summarized.},
doi={10.12691/jfnr-3-5-9}
publisher={Science and Education Publishing}
}