@article{jfnr20142813,
author={{Ji-Lin, Dong and Ying-ying, Zhu and Lin, Li and Rui-ling, Shen and Hong, Li},
title={Effect of Oat Soluble and Insoluble ¦Â-glucan on Lipid Metabolism and Intestinal<i> </i><i>Lactobacillus</i> in High-fat Diet-induced Obese Mice},
journal={Journal of Food and Nutrition Research},
volume={2},
number={8},
pages={510--516},
year={2014},
url={http://pubs.sciepub.com/jfnr/2/8/13},
issn={2333-1240},
abstract={In this study, high-fat diet-induced obese mice were administered oat soluble (SOG) and insoluble ¦Â-glucan (IOG) at different doses. Mice were sacrificed after 6 weeks, body weight, serum lipid level, fecal pH value, fecal bile acid excretion and total colonic short-chain fatty acid (SCFA) concentration was measured. Mesenteric adipocyte count and size were also evaluated histologically. The population of <i>Lactobacillus</i> in colon was determined. Compared with obese mice administered normal saline, body weight, serum cholesterol, triglycerides and the lipoprotein profile were significantly decreased (<i>p</i>&lt;0.05) in mice administered SOG and IOG. The fecal pH value was significantly decreased (<i>p</i>&lt;0.05), while both fecal bile acid excretion and total colonic SCFA concentration were significantly increased (<i>p</i>&lt;0.05). In addition, it exhibited an increase of fat cell count and a decrease of cell size. SOG and IOG restored the number of <i>Lactobacillus</i> in colon (<i>p</i>&lt;0.05). IOG was more effective on weight-loss while SOG might play a more important role in improving serum lipids and the efficacy of promoting growth of <i>Lactobacillus</i> is similar. A dosage of 2 g&#8226;kg<SUP>-1</SUP>&#8226;BW (Body Weight) produced the most significant effect. These data were anticipated to support the prebiotic property and anti-obesity effect of oat ¦Â-glucan.},
doi={10.12691/jfnr-2-8-13}
publisher={Science and Education Publishing}
}