eng Science and Education Publishing Journal of Food and Nutrition Research 2014-02-07 2 1 51 55 10.12691/jfnr-2-1-9 JFNR2014219 article S. Abubakar salisuabubakar99@yahoo.com 1 A. B. Usman 1 I. Z. Ismaila 2 G. Aruwa 2 S. G. Azizat 2 G.H. Ogbadu 2 P.C. Onyenekwe 2 Advance Biotechnology and Genetic engineering laboratory, Sheda Science and Technology Complex, Garki, FCT Abuja Biological Sciences Progarmme, Abubakar Tafawa Balewa University, Bauchi, Bauchi State, Nigeria The work focused on the nutritional and pharmacological potential of Leptadenia hastata (pers.) Decne. ethanolic leaves extract. The proximate compositions of the leaves shows the values of moisture content (7.63 ± 0.07), Ash content (17.19 ± 0.05), Carbohydrate (47.13 ± 0.17), Crude protein (20.85 ± 0.07), Crude fibre (7.50 ± 0.05), and Crude lipid (2.70 ± 0.06). The Phytochemistry of the ethanolic leaves extract divulged the presence of Tannins, Glycosides, Alkaloids, Carbohydrates and Flavonoids. The leaves extract tested possess some decree of antimicrobial activities on Staphylococcus aureus, Escherichia coli, Klebsiella pneumoniae, and Proteus mirabilis at 200 mg/ml and 100 mg/ml respectively. The mineral composition analysed (using Shimadzu AA 6800 Atomic Absorption Spectrophotometer) of the leaves quantified the nutritive elements such as Calcium (23.90 ± 0.01), Magnesium (147.45 ± 0.01), Sodium (1.26 ± 0.01), Iron (0.82 ± 0.00), Zinc (2.30 ± 0.05), Copper (2.86 ± 0.01), Manganese (1.80 ± 0.00), Chromium (0.25 ± 0.00) and potassium (0.18 ± 0.00). While Lead and Cadmium are absent. Nevertheless, the invitro antioxidant potentiality was evaluated using 2, 2-Diphenyl-1-Picrylhydrazyl radical (DPPH Sigma-Aldrich), which shows promising antioxidant activity of the plant leaves extract. http://pubs.sciepub.com/jfnr/2/1/9/jfnr-2-1-9.pdf antibacterialantioxidantElemental analysisLeptadenia hastataPhytochemistryproximate composition