@article{jfnr20231196,
author={{Topete-Betancourt, Alfonso and Mu?oz, Luis E. S¨¢mano and Mart¨ªnez-Flores, H¨¦ctor E. and ¨¢lvarez-Cort¨¦s, Osvaldo and Ortiz, Jose J. Virgen and Garnica-Romo, M.G. and Ortega-Varela, Luis F. and Garc¨ªa-Mart¨ªnez, Rosa M.},
title={Comparison of <i>Cannabis</i> Flower Oil Extract from Microwave, Ultrasound, and Combined Processes: Yield, Cannabinoids Content, and Analgesic Effect in Situ},
journal={Journal of Food and Nutrition Research},
volume={11},
number={9},
pages={594--601},
year={2023},
url={http://pubs.sciepub.com/jfnr/11/9/6},
issn={2333-1240},
abstract={<i>Cannabis</i> <i>Sativa</i><i> </i><i>L.</i> has been studied due to the psychoactive ingredients it contains. Demand for<i> </i><i>Cannabis</i> oil has shown consistent growth since outbreak of the COVID-19 pandemic, and therefore more studies are required to improve or develop new extraction methods. The purpose of this research was to apply microwave combined with ultrasound technologies to enhance the oil extraction yield without compromising quality. Total phenolic and cannabinoid (THC, CBD) compounds content, yield, and analgesic properties were evaluated in the oil samples. The combination of processes showed higher oil yield (48.93%); however, the oil had lower values of THC content (32.14 mg/ml oil), lower analgesic quality, and low DPPH? (1.39 mg/ml) and ABTS?+ (23.37 mg/ml) scavenging activity, as well as low content of total phenol compounds (13.53 mg GAE/g oil) and high peroxide value (9.09 mEq O<SUB>2</SUB>/Kg). The ultrasound process showed 40.36% yield, 1.02 mg/ml DPPH? value, and 2.30 mg/ml ABTS?+, 24.51 mg GAE/oil g total phenolic content, 7.93 meq/ peroxide value, and enhanced analgesic capacity, followed by the values obtained by microwave. The results suggest that ultrasound represents an alternative process to produce <i>Cannabis</i> oil of high quality. In addition, the <i>Cannabis</i> oil had elevated THC content, which could be related to anti-inflammatory capabilities.},
doi={10.12691/jfnr-11-9-6}
publisher={Science and Education Publishing}
}