eng Science and Education Publishing Journal of Food and Nutrition Research 2333-1240 2023-09-08 11 9 564 572 10.12691/jfnr-11-9-2 JFNR20231192 article Sebastian Alberto Ramos-Arcos 1 Sugey L車pez-Mart赤nez sugey.lopez@ujat.mx and sugeylo@hotmail.com 1 Jos谷 R. Vel芍zquez-Mart赤nez 2 Yenny A. G車mez-Aguirre 3 Emmanuel Caba?as-Garc赤a 4 Carlos M. Morales-Bautista 5 Minerva A. Hernandez-Gallegos 6 Divisi車n Acad谷mica de Ciencias Biol車gicas, Universidad Ju芍rez Aut車noma de Tabasco, Villahermosa, M谷xico Divisi車n Acad谷mica de Ciencias Agropecuarias, Universidad Ju芍rez Aut車noma de Tabasco, Villahermosa, M谷xico CONACyT Research Fellow, Universidad Aut車noma de Aguascalientes, Aguascalientes, M谷xico Centro de Estudios Cient赤ficos y Tecnol車gicos No. 18, Instituto Polit谷cnico Nacional, Zacatecas, M谷xico, Divisi車n Acad谷mica de Ciencias B芍sicas, Universidad Ju芍rez Aut車noma de Tabasco, Villahermosa, M谷xico Divisi車n Acad谷mica Multidisciplinaria de Jalpa de M谷ndez, Universidad Ju芍rez Aut車noma de Tabasco, Jalpa de M谷ndez, M谷xico Research was conducted on the biological potential and phenolic composition of Tradescantia zebrina Bosse. Through aqueous and hydroalcoholic extracts of leaves of the species, the total phenolic content (TPC), total flavonoid content (TFC) and total tannin content (TTC) were determined; the antioxidant activity by DPPH?, ABTS?+ and FRAP methods, as well as the biological activities, antibacterial by agar diffusion and minimum inhibitory concentration (MIC), and anti-inflammatory under the 12-O-tetradecanoylphorbol-13-acetate (TPA) method in Institute of Cancer Research (ICR) mice. The hydroalcoholic extract presented the highest TPC (73.07 ± 0.78 mg EAG/g), TFC (24.34 ± 0.68 mg EC/g) and TTC (26.96 ± 0.18 mg EAG/g), and a relevant antioxidant activity with the FRAP assay (353.92 ± 3.20 mM ET/g). In addition, this extract was the only one that presented an inhibition zone of 8.5 ± 1.4 and 8 ± 0.0 mm, against Bacillus cereus and Staphylococcus aureus, respectively. As well as a higher percentage of inhibition of inflammation (47.99%), an approximate value to the reference drug used. The evidence indicates that this plant possessing pharmaceutical potential that can be further explored as a natural source of new drugs. http://pubs.sciepub.com/jfnr/11/9/2/jfnr-11-9-2.pdf Tradescantia zebrina antioxidant antibacterial anti-inflammatory extracts