@article{jfnr20231146,
author={{Derosa, Giuseppe and DĄŻAngelo, Angela and Maffioli, Pamela},
title={Effects on Glyco-Metabolic Control after 12 Months of Treatment with a Supplement of Ilex Paraguariensis, White Mulberry and Chromium Picolinate in Non-Diabetic Patients with Dysglycemia},
journal={Journal of Food and Nutrition Research},
volume={11},
number={4},
pages={319--324},
year={2023},
url={http://pubs.sciepub.com/jfnr/11/4/6},
issn={2333-1240},
abstract={The primary endpoint of the current study was to evaluate whether the effects previously demonstrated in the 3-month study could be maintained for 12 months. Patients were randomized to take Glicoset? in addition to a standardized diet, or to follow a standardized diet alone for 12 months. Glicoset? was self-administered once a day, 1 tablet during the breakfast. After 12 months, 31.9 % of patients retuned to a normal glycemic status in the group treated with nutraceutical + diet vs 3.3 % of patients in diet alone group (p < 0.05). At the end of the study 43.6% were classified as IFG in the group treated with nutraceutical + diet group vs 37% in diet alone group (p < 0.05). In the group treated with nutraceutical + diet, 24.5% were classified as IGT at the end of the study vs 51.1% in diet alone group (p < 0.01). In diet alone group, 8.7% developed type 2 diabetes mellitus vs 0 patients in diet + nutraceutical group (p < 0.05). Total cholesterol, LDL-C, and Tg were lower in the group treated with the nutraceutical combination. The positive effects on glycemic and lipid profile already showed in a 3 months study were also maintained after 12 months of treatment with a nutraceutical containing Ilex Paraguariensis, White Mulberry and Chromium Picolinate.},
doi={10.12691/jfnr-11-4-6}
publisher={Science and Education Publishing}
}