eng Science and Education Publishing Journal of Food and Nutrition Research 2333-1240 2022-08-14 10 8 571 577 10.12691/jfnr-10-8-5 JFNR20221085 article Xianjiang Wen 1 Fida Noor 2 Hafeez Noor 2 Jianxia Wang 3 Chuanming Xiao xcm@keepyoung.com.cn 4 Shanxi Key Laboratory of Sorghum Genetic and Germplasm Innovation, Sorghum Research Institute of Shanxi Agricultural University, Jinzhong 030600, Shanxi Province, People¡¯s Republic of China College of Veterinary Medicine, Shanxi Agricultural University, Taigu, 030801, China Shanghai Genon Biological Product Company, Shanghai 201210, People¡¯s Republic of China Beijing Engineering Laboratory for Function Research and Application Technology of Natural Plant Feed, Beijing Keepyoung The effects of dietary supplementation of plant extract (Impim) on growth performance, immune organ indexes, serum biochemical indicators, and nutrients digestibility of broiler chickens. Nine hundred one-day-old Cobb commercial broilers were randomly allocated into 3 treatments with 3 replicates in each treatment with 100 broilers in each replicate. The 3 dietary treatments were 1) control group (CON), basal diet; 2) CON + 0.02% Impim (Impim group); 3) CON + 0.002% Colistin sulfate premix + 0.004% Aureomycin premix. The trial period were 53 days. The results showed that, compared with antibiotic group, the serum total protein, amylase activity and lipase activity of broilers fed with Impim had been significantly improved by 9.91%, 18.25% and 14.73%, respectively (P < 0.05). In addition, digestibility of Ca, P, CP and ether extraction (EE) were significantly improved by 34.10%, 24.17%, 18.88% and 18.98%, respectively (P < 0.05). Death and culling rate was decreased by 32.09% (P < 0.05), ADG was increased by 2.37% (P < 0.05), feed intake was increased by 0.32% (P < 0.05) respectively, glutamic-pyruvic transaminase (ALT) activity was increased by 2.03% (P < 0.05), and D 42 immune organ indexes was increased (P > 0.05) in broilers of Impim group than antibiotic group. It could be concluded that administration of the Impim to broilers¡¯ diet improved chickens¡¯ growth performance, had a potent immunomodulatory effect (potentiated immune response). Eventually, Impim could be used as a partial replacement to the antibiotics. http://pubs.sciepub.com/jfnr/10/8/5/jfnr-10-8-5.pdf broilers growth performance immune function plant extract