@article{jfnr20221047,
author={{Lin, Yung-Kai and Liang, Chia-Hua and Lin, Yung-Hsiang and Chan, Shu-Ting and Chiang, Chi-Fu},
title={Novel Hydrolyzed Porcine and Fish Collagen Beverage Improved Collagen, Elasticity, Moisture, Spots: A Randomized, Double-blind, Placebo-controlled Trial},
journal={Journal of Food and Nutrition Research},
volume={10},
number={4},
pages={305--312},
year={2022},
url={http://pubs.sciepub.com/jfnr/10/4/7},
issn={2333-1240},
abstract={<b>Background: </b>As the population ages, oral hydrolyzed collagen supplements are gaining traction. However, few clinical studies on the skin health of hydrolyzed porcine collagen combined with fish collagen. <b>Objective: </b>This study investigates whether TripleUp collagen beverage has skincare and anti-inflammatory effects. <b>Methods:</b> Using collagen beverage to treat epidermal keratinocytes and examine ROS, HA, inflammatory factor, and moisturizing-related gene expressions (<i>Tgm1</i><i>, </i><i>Krt14</i><i>, </i><i>FLG-F</i><i>, </i><i>GBA</i><i>, </i><i>HAS3</i>). Fifty subjects were recruited into a placebo and collagen beverage group for four weeks and then examined skin condition at 0, 2, 4 weeks. <b>Results: </b>TripleUp collagen beverage decreased IL-8 and ROS expression and increased moisturizing-related gene expressions. In addition, collagen beverages increase skin collagen, elasticity, moisture, and decreased spots. <b>Conclusions: </b>Thus, TripleUp collagen beverage included hydrolyzed porcine, and fish collagen and vitamin C can improve skin condition.},
doi={10.12691/jfnr-10-4-7}
publisher={Science and Education Publishing}
}