@article{jfnr20221012,
author={{Kim, Min Jung and Park, Kwang-Hyun and Yang, Hye Jeong and Jang, Dai Ja and Lee, Hak Yong and Park, Young Mi and Kim, Byeong Soo and Shin, Dong Yeop},
title={Ameliorative Effects of <i>Schizandra chinensis</i> Extracts and Their Soybean Powder Blends to Diabetes Mellitus},
journal={Journal of Food and Nutrition Research},
volume={10},
number={1},
pages={8--18},
year={2022},
url={http://pubs.sciepub.com/jfnr/10/1/2},
issn={2333-1240},
abstract={<i>Schisandrae chinensis</i> (Omija) is traditionally used as a food-based medicinal/pharmaceutical resources including antidiabetic agent in worldwide. In this study, the optimal combined formula of Omija extract and soybean mixture (OSM) were investigated for its effects on type 2 diabetes model expressed in <i>in Vitro</i> and <i>in Vivo</i> animal model. Using whole extracts, we confirmed inhibitory effects to ¦Á-glucosidase, ¦Á-amylase and the DPPH scavenging <i>in Vitro</i> and examined glucose tolerance in mice. The combined optimum formulation of OSM were significantly ameliorated type 2 diabetes-related. Furthermore, activation of p-Akt, p-AMPK, p-IRS and GLUT2 expression level is pivotal roles of in this anti-diabetic molecular mechanism on <i>in Vivo </i>without side effects. Therefore, these results suggest that OSM is good resources for improves of type 2 diabetes and its complications.},
doi={10.12691/jfnr-10-1-2}
publisher={Science and Education Publishing}
}