@article{jfnr2013121,
author={{Li, Shaoting and Wang, Cong and Peng, Xichun and Wu, Xiyang},
title={Effects of Aqueous Extracts and Essential Oil from <i>Cinnamomum cassia</i> on Rat Colonic Mucosal Morphology and <i>Bacteroidales</i>},
journal={Journal of Food and Nutrition Research},
volume={1},
number={2},
pages={7--12},
year={2013},
url={http://pubs.sciepub.com/jfnr/1/2/1},
abstract={Recently, the preventive effects of <i>Cinnamomum cassia</i> on several metabolic diseases, e.g. obesity, diabetes, hypertension, have been reported. However, no literature reported on the interaction of phytochemicals from <i>C. cassia</i> and colonic microecology.This study aimed to explore the impact of essential oil and aqueous extracts of<i> </i><i>C</i><i>.</i><i> cassia</i><i> </i>on rat colonic mucosal morphology and microbiota. After 4-week feed, the rats administrated with aqueous extracts of <i>C. cassia</i> (AEC) resulted in less body-weight gain (45.33g, <i>P</i>&lt;0.01) and those administrated with essential oil of <i>C. cassia</i> (EOC) had no difference in weight gain compared with controls (85.33g vs. 87.67g, <i>P</i>>0.05). AEC rather than EOC decreased villous area and crypt count of rat colonic mucosa significantly (<i>P</i>&lt;0.01). According to the TRFLP analysis, both of the AEC and EOC increased total peak areas of <i>Bacteroidales</i> (<i>P</i>&lt;0.05), as well as changed terminal restriction fragments in different degrees (mainly 76 bp and 614 bp, <i>P</i>&lt;0.01). AEC altered the tested ratsĄŻ colonic mucosa and community structure of probably obesity-associated gut microbiota (<i>Bacteroidales</i>). This change potentially resulted in a decreased energy harvest from diet as the rats gained less body weight. Despite EOC up-regulated the total amount and diversity of colon <i>Bacteroidales</i>, its influence on weight gain had scarcely been detected.},
doi={10.12691/jfnr-1-2-1}
publisher={Science and Education Publishing}
}