eng Science and Education Publishing Journal of Cancer Research and Treatment 2374-2003 2018-04-17 6 1 25 27 10.12691/jcrt-6-1-5 JCRT2018615 article Ahmed M. Kabel drakabel@gmail.com 1 2 Eman A. Alharthi 3 Rana K. Alshehri 3 Afnan S. Alghamdi 3 Department of Clinical Pharmacy, College of Pharmacy, Taif University, Taif, KSA Pharm D, College of Pharmacy, Taif University, Taif, KSA Indole-3-carbinol (I3C) is a natural agent found in high amounts in cruciferous vegetables and is also available as dietary supplements. It is considered as a promising agent for the ongoing medical research due to its possible antioxidant, anti-inflammatory, anti-tumor, antiapoptotic and anti-atherogenic properties. Recent studies are directed towards assessment of the possible effects of I3C on various body organs including the heart, liver, kidney and the endocrine system. This mini-review sheds light on the different properties of I3C that make it a promising therapeutic agent for a wide variety of human diseases including cancer. http://pubs.sciepub.com/jcrt/6/1/5/jcrt-6-1-5.pdf cruciferous vegetables indole-3-carbinol natural agent cancer