eng Science and Education Publishing Journal of Cancer Research and Treatment 2374-2003 2018-02-27 6 1 6 11 10.12691/jcrt-6-1-2 JCRT2018612 article İlker Kızıloğlu 1 Ahmet Çağdaş Acara cagdasacara@gmail.com 2 Bahattin Bayar 3 Serkan Karaıslı 4 Erdem Sarı 5 Ercüment Tarcan 5 Bozyaka Research and Training Hospital/ Surgent Department of Emergency Medicine, Sağlık Bilimleri University, Faculty of Medicine, Bozyaka Research and Training Hospital, İzmir, Turkey Muş State Hospital/ Surgent Katip Çelebi University Hospital/Surgent Biğadiç State Hospital / Surgent Breast cancer is the second most common type of cancer in the world and it is the most frequently seen cancer type in women. In early stages involving small and monocenter tumors, surgical treatment with breast conserving surgery followed by radiotherapy is the most preferred treatment regimen. Similar to the size of the tumor, several prognostic factors determine survival in breast cancer patients. This study was conducted to evaluate prognostic factors and their relationship to the menopausal status of the patients. University Ataturk Training and Research Hospital, Izmir, Turkey with 573 patients diagnosed with breast cancer between January 2006 and December 2012. Patient age, menopausal status, tumor location surgical treatment information, treatment regimen was gathered using the registry system of the hospital. Male breast cancer patients and patients with insufficient data were excluded. The mean (±SD) age of the study population was determined as 55.9 (±12.9). Most of the patients (65.3%) included in the study were identified as post-menopausal (n=199). Post-menopausal women were detected with larger tumors (p=0.048), at a later stage (p=0.037), with higher KI-67 index (p=0.015) and received more adjuvant hormone therapy (p=0.036) when compared to the pre-menopausal women. Multi-centered studies are needed to evaluate prognostic factors and their relationship to the menopausal status of the patients in order to plan more precise personal treatment regimens. http://pubs.sciepub.com/jcrt/6/1/2/jcrt-6-1-2.pdf breast cancer KI-67 menopausal status