eng Science and Education Publishing Journal of Cancer Research and Treatment 2374-2003 2016-12-22 4 6 96 98 10.12691/jcrt-4-6-1 JCRT2016461 article Ahmed M. Kabel drakabel@gmail.com 1 2 Ali Y. Alghubayshi 3 Fatma M. Moharm 4 Department of Pharmacology, Faculty of Medicine, Tanta University, Tanta, Egypt PharmD candidate, Taif, Saudi Arabia Dermatology specialist, Ministry of Health, Egypt Polycystic ovarian syndrome (PCOS) is a common endocrine disorder in women during their reproductive age. Recent studies showed that PCOS may be a risk factor to the development of endometrial cancer. This risk factor may be associated with sleep disorders including sleep-disordered breathing and excessive daytime sleepiness. The mechanisms leading to this high prevalence of sleep disorders in PCOS have not yet been identified. However, possible causes include alterations in body fat composition due to excess androgen levels and/or the effects of the metabolic syndrome. These effects on sleep disorders may have an impact on daily physical activities. http://pubs.sciepub.com/jcrt/4/6/1/jcrt-4-6-1.pdf PCOS endometrial cancer physical activity sleep