@article{jcrt2015311,
author={{Santana-Blank, Luis and Rodr¨ªguez-Santana, Elizabeth and Santana-Rodr¨ªguez, Karin E. and Santana-Rodr¨ªguez, Jes¨²s A. and Reyes, Heberto},
title={Water¡¯s Many Roles in Laser Photobiomodulation},
journal={Journal of Cancer Research and Treatment},
volume={3},
number={1},
pages={1--5},
year={2015},
url={http://pubs.sciepub.com/jcrt/3/1/1},
abstract={The roles of water and carbon dioxide in laser/light interactions in higher-order biological systems and their implications in cellular microenvironments and complex systemic processes for the restoration of homeostasis-homeokinesis, even when metabolic pathways have been compromised, are discussed. This lecture summarizes three decades of pre-clinical and clinical investigations and the basis for a potentially new therapeutic approach for the treatment of advanced cancer and other complex diseases using laser photobiomodulation. We propose that light-water interactions offer a potent, alternate and complementary pathway to activate and modulate tumor suppression and/or proto-oncogenic expression through energy transfer via water and CO<SUB>2</SUB> in multi-fractal regimes, leading to the coupling of spatiotemporal oscillators. Laser photobiomodulation may, thus, offer the possibility of targeting multiple hallmarks of cancer and other complex diseases using fit-for-purpose electromagnetic (light) energy to restore physiologically reparative and regenerative mechanisms that can help reestablish homeostasis-homeokinesis, constituting a new emerging paradigm in the treatment of cancer and other complex diseases.},
doi={10.12691/jcrt-3-1-1}
publisher={Science and Education Publishing}
}