eng Science and Education Publishing Journal of Biomedical Engineering and Technology 2373-1303 2017-11-21 5 1 25 29 10.12691/jbet-5-1-5 JBET2017515 article I-Lu Chen 1 Yashbir Singh 1 Wei-Chih Hu weichihhu@cycu.edu.tw 1 Department of Biomedical Engineering, Chung Yuan Christian University, Zhongli, Taiwan Most of the epidemiological studies have shown a good relationship between blood pressure and manifestation of cardiovascular diseases (CVD). CVD has become a very common health condition that exhibits significant changes in distensibilility, compliance, and elastic modulus of the arterial vascular system. The main causes of this disease are the spreading of fats and cholesterols which initiate the damaging of endothelium, decreasing wall buffering capacity, and hardening of the arteries eventually leading to severe narrowing. We compared data from invasive and non-invasive blood pressure wave form. Using the Windkessel model, to estimate the arterial compliance as vascular index, we used data after the aortic valve closed to the end-diastolic point of blood pressure waveforms, utilized Bland-Altman difference plot, T-test, box whisker plot and scatter diagram. We analyzed physiological real data and investigated the correlation between the non-invasive and invasive blood pressure wave form. Non-invasive compressive pulse waveforms can be used to assess the total compliance of the arterial blood pressure waveforms of the invasive aorta that indicates the buffering of muscle and adipose tissue. http://pubs.sciepub.com/jbet/5/1/5/jbet-5-1-5.pdf cardiovascular disease arterial compliance Windkessel model non-invasive blood pressure waveform