@article{jaem2021914,
author={{Aghanya, Iloduba Nnaemeka and Akujobi, Comfort Nne and Ushie, Simon Nkpeh and Ubajaka, Chika Florence and Ajuba, Ijeoma Maryrose and Ezeama, Chibuike Jesse and Maduekwe, Nkechi Perpetua and Uzoewulu, Ngozichukwu Gertrude and Chigbo, Chisom Godswill},
title={Carbapenemase-producing <i>Klebsiella pneumoniae</i> Isolated from Environmental Sources in a Tertiary Health Institution in Nigeria},
journal={Journal of Applied & Environmental Microbiology},
volume={9},
number={1},
pages={22--27},
year={2021},
url={http://pubs.sciepub.com/jaem/9/1/4},
issn={2373-6712},
abstract={The acquisition of carbapenemase-producing organisms in healthcare settings is a significant threat and has dire implications for public health. Previous reports regarding carbapenemase-producing <i>Enterobacteriaceae</i> from fomites are limited. This study aimed to analyse the antimicrobial resistance patterns and prevalence of carbapenemase-producing <i>Klebsiella pneumoniae</i> in the ward environments of a tertiary health institution in Nigeria.One hundred and forty-two bacteria were isolated from 534 fomites in the hospital wards, and out of these, 15(10.6%) were <i>K. pneumoniae</i>. Therefore, the prevalence of <i>K. pneumoniae</i> in all the samples was 15/534(2.8%), while that of carbapenemase-producing <i>K. pneumoniae </i>was 8/534(1.5%). Multi-drug resistance was detected in 15/15(100%) of the <i>K. pneumoniae </i>isolated. All the <i>K. pneumoniae </i>isolates were resistant to ampicillin, trimethoprim-sulfamethoxazole, cefuroxime, and tetracycline. Although 8/15(53.3%) of the isolates were confirmed positive for carbapenemase production using the modified Hodge test, no <i>Klebsiella pneumoniae </i>carbapenemase gene (<i>bla</i><SUB>KPC</SUB>) was detected. The most frequent sites that harboured carbapenem-resistant <i>K. pneumoniae </i>were the beds 6/15(40%). Hence, the prevalence of carbapenemase-producing <i>K. pneumoniae </i>fomite colonisation in the NAUTH ward environment was low.},
doi={10.12691/jaem-9-1-4}
publisher={Science and Education Publishing}
}