eng Science and Education Publishing International Journal of Hematological Disorders 2017-03-13 3 1 1 2 10.12691/ijhd-3-1-1 IJHD2017311 article Ines Safra ines.safra@pasteur.rns.tn 1 Imene Namouchi 1 HMC Laboratory 1 Salem Abbes 1 Samia Mnif 1 University of Tunis El Manar, Medecine Tunis Faculty, HMC Laboratory, Pasteur Institute of Tunisia Idiopathic CD4+ lymphocytopenia (ICL) is a syndrome first defined in 1992 by the Centers for Disease Control and Prevention (CDCP) as Ą°a documented absolute CD4 T lymphocyte count of less than 300 cells per cubic millimeter or of less than 20% of total T cells on more than one occasion, no evidence of infection on HIV testing and the absence of any defined immunodeficiency or therapy associated with depressed levels of CD4 T cellsĄ±. The clinical course, immunologic characteristics, CD4 T cell kinetics, long term outcome and prognosis of this syndrome remain poorly defined but it is widely accepted that ICL is a rare, heterogeneous syndrome, usually detected after the occurrence of an opportunistic infection in a person without known immunodeficiency or immunodepression although it can also be an incidental laboratory finding. Autoimmune phenomena are common in this syndrome. In this article, we reported a case diagnosed with an EvansĄŻ syndrome and that fulfilled the CDCP definition of ICL. http://pubs.sciepub.com/ijhd/3/1/1/ijhd-3-1-1.pdf thrombocytopenia anemia immune defeciency Fow cytometry