@article{ijhd20141111,
author={A.J, Esan},
title={Effect of G<SUB>6</SUB>PD Status in Malaria Infected Individuals on Haematological Parameters},
journal={International Journal of Hematological Disorders},
volume={1},
number={1},
pages={55--57},
year={2014},
url={http://pubs.sciepub.com/ijhd/1/1/11},
abstract={The aim of this study was to determine the effect of G<SUB>6</SUB>PD status no haematological parameters in Plasmodium falciparum malaria infected and non-malaria infected individuals. The study was conducted at Federal Teaching Hospital, Ido-Ekiti, Nigeria. Malaria infected adult individuals; presented with signs and symptoms of malaria infection was used for the study. Two hundred and two blood samples were collected twice from the same malaria infected individuals; grouped as pre-treatment and post anti-malaria drug treatment. One hundred and two blood samples from apparently healthy individuals were collected for control; 5 ml of blood sample was collected and dispensed into di-potassium ethylenediaminetetracetic acid (K<SUB>2</SUB>EDTA) vaccutainer bottles for haemoglobin concentration, packed cell volume and red cell indices were analysed using haematology analyser, thick blood film was made and stained with Giemsa¡¯s staining technique for malaria parasite detection, the procedure was described by Monica Cheesbrough. Glucose-6-Phosphate dehydrogenase (G-6-PD) was performed using methaemoglobin reduction method within 6 hours of sample collection. The procedure was as described by Dacie and Lewis. Data obtained was analysed using SPSS version 16. The result of this present study showed that, the mean¡ÀSD of Hb, PCV, MCV and MCH were significantly (P&lt;0.05) lower in G<SUB>6</SUB>PD normal compared to G<SUB>6</SUB>PD deficient in pre and post anti-malaria drug treatment while mean¡ÀSD of RBC, Hb and PCV were significantly (P&lt;0.05) higher in G<SUB>6</SUB>PD normal compared to G<SUB>6</SUB>PD deficient in control subjects. This present study showed that malaria attack in G<SUB>6</SUB>PD normal was observed more intensive compared to G<SUB>6</SUB>PD deficient.},
doi={10.12691/ijhd-1-1-11}
publisher={Science and Education Publishing}
}