@article{ijdsr2021924,
author={{Shuker, Arjwan M. and Al-Wattar, Wael T. and Taha, Mahmoud Y.M.},
title={Estimation of Interleukin 8 in Aphthous Ulceration},
journal={International Journal of Dental Sciences and Research},
volume={9},
number={2},
pages={37--41},
year={2021},
url={http://pubs.sciepub.com/ijdsr/9/2/4},
issn={2333-1259},
abstract={Recurrent aphthous ulceration (RAU) is an acute inflammatory disease affecting oral mucosa. It has been reported that cytokines such as IL2, TNF ¦Á, IL6 were produced in patients with RAU. IL8 is a neutrophil chemotactic factor and its level increases in response to virus and bacterial products and TNF ¦Á or IL1¦Â production. The aim of the study was to estimate the concentration of IL-8 in RAU patients compared to control group. The study was carried out on a total number of 70 individuals of both sexes and different age groups (50 patients and 20 control ) attending Department of Oral Surgery, Unit of Oral Medicine, College of Dentistry /Mosul University for the period from 1/10/2017 to 1/4/2018. Clinical examination was performed and blood samples collected, serum was separated and used in ELISA test to estimate IL-8 concentration. The location of RAU was common in the lower lips followed by buccal mucosa. The concentration of IL-8 in RAU patients was highly significant compared to control group. Within different age groups, IL-8 was higher in age group 13-30 years old. Also high concentration of IL-8 was noticed in females more than males. Minor RAU showed higher concentration of IL-8.},
doi={10.12691/ijdsr-9-2-4}
publisher={Science and Education Publishing}
}