eng Science and Education Publishing International Journal of Dental Sciences and Research 2333-1259 2021-01-20 9 1 15 19 10.12691/ijdsr-9-1-4 IJDSR2021914 article Hanin Alsalhi dr.haneen.alsalhy@qudent.org 1 Nasser Alkatheeri 2 Restorative Dental Science Department, College of Dentistry, Qassim University, Qassim, Saudi Arabia Endodontic Department, National Guard Health Affair, Riyadh, Saudi Arabia Endodontic intervention in necrotic immature permanent teeth is usually a clinical challenge. With appropriate case selection and optimal disinfection, regenerative endodontic procedure (REP) can be effective and a desirable result can be obtained. In this report, an immature necrotic mandibular second molar had been treated by REP in two visits. In the first visit, a nonsetting calcium hydroxide was used as intracanal medication after irrigation with 1.5% (NaOCl). In the second visit, blood clots were created in the root canals. MTA was placed over the blood clots and the tooth was restored with a composite filling and stainless-steel crown. A clinical and radiographic follow up was performed for three years where the tooth was deemed a symptomatic with a complete root formation. http://pubs.sciepub.com/ijdsr/9/1/4/ijdsr-9-1-4.pdf revascularization regenerative endodontic procedure Calcium hydroxide immature tooth