eng Science and Education Publishing International Journal of Dental Sciences and Research 2333-1259 2019-02-05 7 1 10 17 10.12691/ijdsr-7-1-3 IJDSR2019713 article Neven S. Aref flflaref@gmail.com 1 2 Mohamed M. Said 3 Rasha H. El-Mahdy 4 Noha A. El-Wassefy 4 Dental Biomaterials Department, Faculty of Dentistry, Mansoura University, Mansoura, Egypt Removable Prosthodontics Department, Faculty of Dentistry, Mansoura University, Mansoura, Egypt Microbiology and Immunology Department, Faculty of Medicine, Mansoura University, Mansoura, Egypt Objective: This study evaluated ginger modified heat cured poly methyl methacrylate (PMMA) denture base material regarding; surface roughness, flexural strength, antimicrobial activity, and color stability. Materials and methods: Ginger was used in powder and oil forms to modify the polymer and monomer. Seven experimental groups were formulated; Group (I) control; Group (II) 3 wt% ginger-powder modified polymer; Group (III) 5 wt% ginger-powder modified polymer; Group (IV) 3 v/v% ginger-oil modified monomer; Group (V) 5 v/v% ginger-oil modified monomer; Group (VI) 3 wt% ginger-powder modified polymer mixed with 5 v/v% ginger-oil modified monomer; Group (VII) 5 wt% ginger-powder modified polymer mixed with 3 v/v% ginger-oil modified monomer. Specimens were tested for surface topography, surface roughness, flexural strength, antimicrobial activity, and color stability. The data were statistically analyzed by one-way ANOVA and post-hoc LSD analysis with a significance factor of α = 0.05. Results: The PMMA polymer modified with 3 v/v% ginger-oil (Group IV) exhibited a significant reduction in surface roughness, a significant increase in flexural strength with clinically acceptable color change. No antimicrobial activity was detected for any of the evaluated groups. Conclusions: 3 v/v% ginger-oil was able to improve the mechanical properties of heat cured PMMA denture base resin with a tolerable color change. http://pubs.sciepub.com/ijdsr/7/1/3/ijdsr-7-1-3.pdf flexural strength ginger PMMA reinforced surface roughness