eng Science and Education Publishing International Journal of Dental Sciences and Research 2333-1259 2018-05-15 6 3 83 87 10.12691/ijdsr-6-3-6 IJDSR2018636 article Mohamed Y Abdelfattah m.yousef@tudent.edu.sa 1 2 Ahmed Abdelaziz Mohamed Essa 3 Mohammed K Fahmi 4 Prosthodontic Department, Faculty of Dentistry, Tanta University, Tanta, Egypt Oral Pathology Department, Faculty of Dentistry, Tanta University, Tanta, Egypt Restorative and Dental Materials Department, Faculty of Dentistry, Taif University, Taif, KSA Objectives: Candida-induced denture stomatitis can be treated with different approaches; one of the most effective methods is the Photodynamic therapy (PDT). The current study aimed to assess the collective effects of PDT and low-level laser therapy (LLLT) in comparison to the topical application of miconazole gel. Materials and Methods: Thirty complete denture wearers with a history of Candida-induced denture stomatitis were haphazardly divided into two groups 15 patient each. Group I: The patients were subjected to a session of methylene blue-mediated PDT followed by to 2 sessions of (LLLT) 2 times per week for 15 days, while those of Group II: were subjected to miconazole gel four times per day for fifteen days. Results: The clinical and cytolological findings revealed that 50% of the patients in Group I have been cured from denture stomatitis while in Group II the curing rate was 85%. After two weeks following treatment stoppage, 30% of Group I patients showed reappearance of symptoms while the ration of recurrence was 15% in Group II patients. Conclusion: Photodynamic therapy associated with low level laser therapy (LLLT) and Miconazole gel can be considered effective methods in the management of Candida-induced denture stomatitis with higher curing rate and lower recurrence ratio for Miconazole. http://pubs.sciepub.com/ijdsr/6/3/6/ijdsr-6-3-6.pdf photodynamic therapy miconazole denture stomatitis