@article{ijdsr2017525,
author={Abdelhamid, Alaa},
title={Effect of Vascular Endothelial Growth Factor Expression in the Destruction and Healing Stages of Chronic Periodontal Disease: A Case Report},
journal={International Journal of Dental Sciences and Research},
volume={5},
number={2},
pages={35--38},
year={2017},
url={http://pubs.sciepub.com/ijdsr/5/2/5},
issn={2333-1259},
abstract={Vascular endothelial growth factor (VEGF) is a homodynamic protein produced by different cells as endothelial cells, macrophages, T-cells. In epithelial and endothelial cells, VEGF has been reported more in periodontitis than in sites with gingivitis, suggesting that it could be a crucial factor for the initiation of gingivitis and its transition to periodontitis. <b>Objective</b>: To determine the effect of non-surgical periodontal treatment on VEGF expression on gingival tissues with chronic periodontitis. <b>Methods</b>: Gingival samples (2-3 mm) were collected immediately before and 4 weeks after non-surgical periodontal therapy from a 48-year-old male with chronic periodontitis. The samples were treated with immunohistochemically. <b>Results</b>: A decrease in VEGF expression was observed in gingival tissues following non-surgical periodontal treatment. <b>Conclusion</b>: VEGF is continually produced and expressed in healthy and diseased gingival tissues; non-surgical periodontal therapy with antibiotics combination significantly affects the expression pattern of VEGF as a biomarker.},
doi={10.12691/ijdsr-5-2-5}
publisher={Science and Education Publishing}
}