Science and Education Publishing International Journal of Dental Sciences and Research 2 6 2014 11 30 Adenosquamous Carcinoma in Buccal Mucosa-A Case Report 158 160 EN Gopal Chandra Halder Jay Gopal Ray Oral and Maxillofacial Pathology, Dr. R. Ahmed Dental College and Hospital, West Bengal University of Health Sciences, Kolkata Santanu Patsa IJDSR2014269 10.12691/ijdsr-2-6-9 2014 11 01 2014 11 25 2014 11 30 Adenosquamous carcinoma is a rare malignant tumor with poor prognosis that is characterized histopathologically by the simultaneous presence of distinct areas of adenocarcinoma and squamous cell carcinoma. Until 2004, only 59 cases of adenosquamous carcinoma have been documented in English literatures in the head and neck region since the first one being reported in 1968. The present report is a case of adenosquamous carcinoma in a 75 years old man with a fast enlarging ulcerated lesion on right buccal mucosa. The patient developed trismus due to local infiltration of tumor mass within the muscle with fixation of the skin and a small perforation on the right side of the face. Adenosqamous carcinoma in the oral cavity is not seen frequently. All the reported cases are in the tongue, floor of the mouth and tonsillar palatine region in descending order. This presentation in the buccal mucosa with infiltration up to the skin is in itself significant and rare.