eng Science and Education Publishing International Journal of Dental Sciences and Research 2014-11-09 2 6 137 140 10.12691/ijdsr-2-6-4 IJDSR2014264 article Nitesh kumar Sharma drniteshsharma@yahoo.com 1 Roopa D.A. 1 Department of periodontics and oral implantology, Rama dental college hospital & research centre, Kanpur Antihypertensive drugs in the calcium channel blocker group are extensively used in elderly patients. Gingival enlargement associated with Nifedipine was first reported in 1980's and is very rarely reported to be associated with Amlodipine and Felodipine. The mechanism through which these medications trigger a connective tissue response are still poorly understood. The most effective treatment of drug induced gingival overgrowth is withdrawl or substitution of medication combined with meticulous oral hygiene, plaque control, and removal of local irritants. When these measures fails to resolve the enlargement, surgical intervention is recommended. This case reports a rare case of Amlodipine induced gingival enlargement. The patient was successfully managed by drug substitution and nonsurgical periodontal terapy. http://pubs.sciepub.com/ijdsr/2/6/4/ijdsr-2-6-4.pdf Nonsurgical therapy Amlodipine Calcium cannel blocker drug induced gingival enlargement