eng Science and Education Publishing International Journal of Dental Sciences and Research 2014-08-18 2 4B 7 10 10.12691/ijdsr-2-4B-3 IJDSR201424B3 article Archana 1 Sasireka 2 M.N Prabhu 3 Bobby bobbds2000@gmail.com 3 Venkata Srikanth 3 Department of Periodontics, Madha Dental College, Chennai,India Department of Periodontics, Adhiparasakthi Dental College, Melmaruvathur, India Departmentof Periodontics, Penang International Dental College, Malaysia Interleukin (IL)-10 is an important immunoregulatory cytokine produced by many cell populations. Its main biological function seems to be the limitation and termination of inflammatory responses and the regulation of differentiation and proliferation of several immune cells such as T cells, B cells, natural killer cells, antigen-presenting cells, mast cells, and granulocytes. The present study has correlated the salivary IL-10 levels with that of the circulatory levels in periodontal health and diseased patients and also brings an attestation for Saliva as point of care diagnosis. http://pubs.sciepub.com/ijdsr/2/4B/3/ijdsr-2-4B-3.pdf interleukins pro inflammatory cytokines anti inflammatory cytokines Th₁ Th₂ GCF