eng Science and Education Publishing International Journal of Dental Sciences and Research 2333-1259 2023-06-13 11 1 8 14 10.12691/ijdsr-11-1-3 IJDSR20231113 article Mohammed Al Ghamdi dentist.mohammed@hotmail.com 1 Nada Shokair 2 Saleh Al Qahtani 3 Abdulrahman Abusaq 4 Roula Albounni 5 Dental Specialist, North Jeddah Speciality Dental Center, Jeddah, 23532; Saudi Arabia Dental Specialist, Tabuk Speciality Hospital, Tabuk, 47324; Saudi Arabia Dental Specialist, Ahad Rufaida General Hospital, Abha, 62523; Saudi Arabia Dental Specialist, Najran Specialized Dental Center, Najran, 66248; Saudi Arabia Department of Operative and Aesthetic Dentistry, Riyadh Elm University, Riyadh, 12734, Saudi Arabia This study aimed to compare the colour changes of resin-infiltrated white spot lesions after exposure to artificial saliva and oral rinses (Oral-B Pro-Expert, Listerine and Colgate Plax) at different time intervals (24 h, 72 h and 7 d). The premolar teeth were selected and sectioned into two halves. The artificial white spot lesions were created and resin-infiltration procedure was performed to seal the pores. The specimens immersed in the control subgroup showed an insignificant colour change (?E) after 72 h. While significant differences in colour change among the experimental groups across time intervals (p<0.001), oral rinse groups (p<0.001), and the interaction between timeline and groups (p<0.001). All resin-infiltrated specimens showed colour differences after immersion in oral rinses with visually perceptible change. Although, Colgate Plax and Oral B oral rinses demonstrated the highest and lowest colour change, respectively in the initial 24 h. However, at 72 h and 7 d time-points, Listerine oral rinse demonstrated the highest colour change, while the lowest values were observed in Oral-B oral rinse. The use of Listerine should therefore be cautiously advised in resin-infiltrated cavities. http://pubs.sciepub.com/ijdsr/11/1/3/ijdsr-11-1-3.pdf color change oral rinses resin-infiltration white spot lesion