@article{ijcen2022911,
author={{AlHussein, Hassan and Raza, Syed Ali and Kelley, Roger E.},
title={Stiff Person Syndrome Overlapping with Multiple Sclerosis},
journal={International Journal of Clinical and Experimental Neurology},
volume={9},
number={1},
pages={1--3},
year={2022},
url={http://pubs.sciepub.com/ijcen/9/1/1},
issn={2379-7797},
abstract={We report the apparent rare association of longstanding relapsing/remitting multiple sclerosis and stiff person syndrome. This middle-aged woman presented with truncal and lower extremities stiffness and spasm not responsive to a course of intravenous methylprednisolone or to high dose muscle relaxants. Her discomfort had progressed, over a one-month period, to being wheelchair bound and considering herself desperate for some type of relief. Of interest, she pursued the medical literature, as a registered nurse, and became convinced that she has stiff person syndrome superimposed on her multiple sclerosis which has not been previously reported. She was found to have an elevated anti-glutamic acid decarboxylase (GAD)-65 antibody titer supporting this association. She was responsive, at least over the short term, to a course of intravenous gamma globulin along with the addition of dantrolene to her regimen.},
doi={10.12691/ijcen-9-1-1}
publisher={Science and Education Publishing}
}