eng Science and Education Publishing International Journal of Celiac Disease 2334-3486 2020-12-01 8 4 120 123 10.12691/ijcd-8-4-2 IJCD2020842 article Aaron Lerner aaronlerner1948@gmail.com 1 Joz¨Ślio Freire de Carvalho 2 Chaim Sheba Medical Center, The Zabludowicz Research Center for Autoimmune Diseases, Tel Hashomer, Israel Institute for Health Sciences from Federal University of Bahia, Salvador, Bahia, Brazil The chain of events, starting from nutrients that change microbiome/dysbiome ratio followed by their secreted mobilome and ending with the leaky gut syndrome, can be applied for cardiovascular diseases. The Gut-heart axis is only one avenue where intestinal luminal eco-events induce remote organ's pathology. The present editorial highlights the mechanisms and potential pathways in the nutrients-microbiota-endocrine-cardiovascular axis that might affect human heart morbidity and mortality in celiac disease. http://pubs.sciepub.com/ijcd/8/4/2/ijcd-8-4-2.pdf celiac disease cardiovascular disease microbiome dysbiome metabolome nutrition gut-heart axis leaky gut nutritional deficiency