eng Science and Education Publishing International Journal of Celiac Disease 2334-3486 2017-06-02 5 2 81 82 10.12691/ijcd-5-2-3 IJCD2017523 article Mohammed Elhassan melhassan@fresno.ucsf.edu 1 Guha Venkatraman 2 Department of Medicine, University of California in San Francisco (UCSF)/Fresno, Fresno, CA, USA Department of Medicine, St. Barnabas Medical Center, Livingston, NJ, USA Celiac disease, or celiac enteropathy, is a relatively common autoimmune disease with myriad of presentations, including intestinal and extra-intestinal manifestations. It is also a less common cause of cerebral white matter lesions in the absence of other etiologies. If such patients are symptomatic, diagnosis can be challenging, especially when gastrointestinal symptoms are absent. The differential diagnosis in such cases is wide and high index of suspicion is needed to make the diagnosis. We presented a case of celiac disease who presented with neurological symptoms and white matter lesions in brain magnetic resonance imaging without gastrointestinal symptoms. http://pubs.sciepub.com/ijcd/5/2/3/ijcd-5-2-3.pdf celiac disease leukoencephalopathies