eng Science and Education Publishing International Journal of Celiac Disease 2334-3486 2016-05-28 4 2 74 76 10.12691/ijcd-4-2-8 IJCD2016428 article Laura Mihaela Trandafir 1 Oana Teslariu 1 Smaranda Diaconescu turti23@yahoo.com 1 Magda Iorga 1 Ingrith Miron 2 Ioan Sarbu 3 Iulia Carmen Ciongradi 3 Department of Pediatric, "Grigore T. Popa" University of Medicine and Pharmacy - Iasi, Romania Department of Pharmacology, "Grigore T. Popa" University of Medicine and Pharmacy - Iasi, Romania Department of Pediatric Surgery and Orthopedics,"Grigore T. Popa" University of Medicine and Pharmacy - Iasi, Romania Celiac disease is an intestinal autoimmune disease induced by the ingestion of gluten proteins (wheat, rye, barley) in genetically susceptible individuals. Celiac disease can present with gastrointestinal or extraintestinal manifestations (malabsorbtion, diarrhea, constipation, liver, skin or bones disorders). We present the case of a 14-months-old girl admitted for altered general condition and symptoms of intestinal occlusion (severe abdominal pain, absence of feces, abdominal distension), with associated severe malnutrition. History revealed chronic diarrhea and a lactose intolerance diagnosed 3 months prior to admission. The biochemical and imaging investigations excluded any acute surgical pathology. The serological tests showed high values of anti-tissue transglutaminase antibodies. The intestinal biopsy confirmed celiac disease. In children with suspicion of intestinal obstruction associated with a history of diarrhea or constipation and failure to thrive, testing for celiac disease should be considered. http://pubs.sciepub.com/ijcd/4/2/8/ijcd-4-2-8.pdf celiac disease children anti-tissue transglutaminase antibodies Pediatric Surgery Unit