eng Science and Education Publishing International Journal of Celiac Disease 2334-3486 2016-05-28 4 2 61 63 10.12691/ijcd-4-2-10 IJCD20164210 article Gabriel Samasca 1 Pirvan Alexandru 2 Genel Sur 2 Abrudan Carmen 3 Iulia Lupan iulia.lupan@gmail.com 4 Diana Deleanu 4 Department of Immunology and Allergology, Iuliu Hatieganu University of Medicine and Pharmacy, Cluj-Napoca, Romania Department of Pediatrics II, Iuliu Hatieganu University of Medicine and Pharmacy, Cluj-Napoca, Romania Emergency Hospital for Children, Cluj-Napoca, Romania Institute for Interdisciplinary Research in Bio-Nano-Science, 'Babes-Bolyai' University, Cluj-Napoca, Romania The celiac disease screening with IgA tissue transglutaminase antibodies depends on the cut-off reaction, therefore many patients with values less but close to the cut-off may be undiagnosed. Material and Method. We conducted the CD screening with IgA tissue transglutaminase antibodies in a group of 1616 children during 2014 at a cut-off of 25 U/ml and at a cut-off of 10 U/ml. We also wanted to compare our results with IgA tissue transglutaminase antibodies prevalence from other countries. Results. We found a IgA tissue transglutaminase antibodies prevalence rate of 3% for values higher 25 U/ml and a IgA tissue transglutaminase antibodies prevalence rate of 1.6% for values between 10-25 U/ml. A prevalence of 13.6% for IgA tissue transglutaminase antibodies was observed in , and . Conclusions. We observed a 4.6% IgA tissue transglutaminase antibodies prevalence at a cut-off of 10 U/ml. Prevalence of IgA tissue transglutaminase antibodies from Romania is lowered compared with other European countries. http://pubs.sciepub.com/ijcd/4/2/10/ijcd-4-2-10.pdf celiac disease screening cut-off