eng Science and Education Publishing International Journal of Celiac Disease 2334-3486 2023-09-04 11 1 9 18 10.12691/ijcd-11-1-3 IJCD20231113 article Dalia Alemam 1 Wamda Alemam wamdaalemam2000@gmail.com 2 Hala Abu El Hassan 3 MBBS University of Juba, MD of Internal Medicine Sudan Medical Specialization Board Faculty of Medicine University of Khartoum, Khartoum State, Sudan MBBS Faculty of Medicine University of Khartoum, MD of Internal Medicine Sudan Medical Specialization Board, MRCP, Consultant Gastroenterologist, Research Supervisor Introduction: The study was conducted at Ibn Sena Hospital during the period from October 2020 to February 2021. The study included 84 patients with celiac disease (CD), of which 28 (33.3%) were males and 56 (66.7%) were females. The average age among the study participants was 30.2±10.3 years. average BMI was 23.8± 3.8. Methodology: This study is a descriptive and analytical, cross sectional, hospital-based study, that went from October 2020 to February 2021 at Ibn Sena hospital. A structured questionnaire was used to collect data about demographic, clinical, and laboratory findings of patients. Then, the data was analyzed using SPSS version 25. Results: The most common GI symptoms were weight loss, diarrhea/steatorrhea, and bloating (61.9%, 58.3%, and 44%, respectively). On the other hand, the most common extraintestinal symptoms are bone and joint pain (58.3%), shortness of breath (52.4%), and anxiety (41.7%). Anemia was present in 86.9% and Calcium levels were low in 98.8% of patients. Depression was prevalent among 28.6% of CD patients. There was significant difference between genders and depression and anemia (P=0.04, P<0.001). Conclusion: Significant difference was found between genders when it comes to depression and anemia, with females having higher risks. http://pubs.sciepub.com/ijcd/11/1/3/ijcd-11-1-3.pdf celiac disease clinical characteristics Sudanese patients