@article{env2014242,
author={{Nevenka, Velickova and Nikola, Kamcev},
title={Genotoxicological Effects of Heavy Metals on Humans Cells},
journal={American Journal of Environmental Protection},
volume={2},
number={4},
pages={71--73},
year={2014},
url={http://pubs.sciepub.com/env/2/4/2},
issn={2328-7233},
abstract={<b>Aims of this study</b> was to detect cytogenetic damage in<SUP> </SUP>mine workers working in a lead¨Czinc mine, which could<SUP> </SUP>be associated with a combined exposure to lead, zinc and cadmium. <b>Methods:</b> This study involved 120 mine workers from the lead¨Czinc<SUP> </SUP>mine in Macedonia, and a control group (30) of local<SUP> </SUP>people who had never worked in the mine. The authors used peripheral blood lymphocytes as the target material.<SUP> </SUP>The total share of structural chromosome aberration (SCA) were searched out over the 3 years of monitoring. Also they measured the blood level of lead, zinc and cadmium with ISP-AES. <b>Results: </b>The authors concluded increased blood lead level in the exposed group (Mean= O,089mg/l) and in 20% in the control group (Mean=0,066mg/l); increased zinc blood level in the exposed (Mean=1,391mg/l) and in control group (Mean=1,074mg/l); increased cadmium blood level in 62% of the exposed (Mean=0,007mg/l) and in 50% of the control group (Mean=0,006mg/l); Chromosomal aberrations (like dicentric and acentric chromosome) were found to be elevated in 7% of exposed individuals (mine workers) non in the control group. Both chromosome type aberrations in the exposed group were accompanied with anemia, leucocitosis and anisocitosis. <b>Conclusion: </b>The group of exposed people showing increased levels of chromosome abnormalities has a higher risk of developing cancer and other deseasses.},
doi={10.12691/env-2-4-2}
publisher={Science and Education Publishing}
}