@article{education2021935,
author={{Nso, Nso and Nassar, Mahmoud and Ojong, Gilbert and Nyabera, Akwe and Lakhdar, Sofia and Alshamam, Mohsen and Nwokoye, Somtochukwu and Li, Matthew and Alfishawy, Mostafa and Brennessel, Debra J.},
title={Thrombosis in Covid-19 Patients and Dilemma of Antithrombotic Choice: A Systematic Review},
journal={American Journal of Educational Research},
volume={9},
number={3},
pages={117--124},
year={2021},
url={http://pubs.sciepub.com/education/9/3/5},
issn={2327-6150},
abstract={Background: Coronavirus Disease 2019 (COVID-19) potentially deteriorates the immune system and triggers prothrombotic states in many patient scenarios. Clinical studies so far do not stratify the risk of thromboembolism in COVID-19 cases. Objective: This systematic review investigates the risks of thromboembolism and outcomes of anticoagulation therapy in COVID-19 patients. Methods: We searched PubMed, Cochrane Library, Embase, Web of Science, and Google Scholar to identify relevant studies assessing thromboembolism and anticoagulant therapy in COVID-19 patients. Study Selection, Data Extraction, and Synthesis: Two reviewers screened the titles and abstracts of the included studies in the context of COVID-19, thrombosis, and anticoagulant therapy. The reviewers also ascertained the elimination of duplicate articles.  Results: We included eight studies based on the thromboembolism predisposition of COVID-19 (adult/elderly) patients with the status/history of cardiovascular disease, diabetes, hypertension, obesity, and hospital admission. Conclusion: Prospective studies need to explore the risks of thromboembolism in patients with COVID-19. The current body of evidence does not substantiate antithrombotic treatment for managing thromboembolism in the setting of COVID-19. The physicians must take preventive measures for reducing the incidence rate of thromboembolism in COVID-19 scenarios until the availability of definitive treatment.},
doi={10.12691/education-9-3-5}
publisher={Science and Education Publishing}
}