eng Science and Education Publishing American Journal of Educational Research 2327-6150 2020-06-08 8 6 391 399 10.12691/education-8-6-5 EDUCATION2020865 article KAREEM Adeyinka Oluwaseun adeyinkareem@gmail.com 1 ADELEKE Moruf Ademola 1 Department of Science and Technology Education, Obafemi Awolowo University, Ile-Ife, Nigeria The study determined the level of Process Skills Application (PSA) and utilization of Higher Order Thinking Skills (HOTS) among Biology students in colleges of education in southwestern Nigeria as well as the relationship between the PSA and HOTS of Biology students in colleges of education in the study area. The population comprised of all Biology students in colleges of education in southwestern Nigeria. One hundred students were selected from each of two federal colleges and three state colleges of education in the study area making a total of five hundred students. Thirty students were randomly selected for observation for process skills application of the students. The study revealed that there was a moderate level of PSA while the utilization of HOTS among the respondent was low. It was also revealed that there was no significant relationship between process skill application and higher order thinking skills (r=0.10, p>0.05) of Biology students in the study area. http://pubs.sciepub.com/education/8/6/5/education-8-6-5.pdf process skill application higher order thinking skills colleges of education