Science and Education Publishing American Journal of Educational Research 2327-6150 5 2 2017 2 22 Evaluate the Effectiveness of Clinical Simulation and Instructional Video Training on the Nursing Students' Knowledge about Cardio-Pulmonary Resuscitation: Comparative Study 172 178 EN Murad Alkhalaileh Adult Health Nursing, Fakeeh College for Medical Sciences, Nursing Department, Jeddah, Kingdom of Saudi Arabia Abd Al-Hadi Hasan Omar Al-Rawajfah EDUCATION20175210 10.12691/education-5-2-10 2016 9 6 2016 12 16 2017 2 20 Aims: To evaluate the effectiveness of instructional video training method of teaching about CPR in comparison with conventional format. Methods: A quasi-experimental design was conducted with 210 students. Students were randomly assigned to receive instructional video training (n = 111) or conventional format of teaching (n = 90). The primary outcome measure was the baseline to endpoint change in knowledge level. Results: A significantly higher overall post-test score was observed for instructional video training group as compared to lecture. Conclusions: instructional video training is as effective as conventional format of teaching in teaching and learning basic emergency skills.