eng Science and Education Publishing Biomedicine and Biotechnology 2013-11-15 1 2 11 16 10.12691/bb-1-2-3 BB2013123 article AyyadWajeeh Raaof ayyadalshahwany@yahoo.com 1 Zahraa Abdul-Elah Al-Naqqash 2 Abdul-Latif M. Jawad 2 Salah M. Muhsan 3 Department of Biology, College of Science, Baghdad University, Baghdad, Iraq College of Pharmacy, Al-Mustansyria University, baghdad, Iraq Biotechnology research center, Al.Nahrain University, Baghdad, Iraq As Alkaloids known for their pharmaceutical importance; this research included the extraction of crude alkaloids of three plants (Zingiberofficinale Roscoe, Thymus vulgaris L. and Acaciaarabica L.) and evaluate their activity as coagulant agent by using three degraded concentrations of each plant extract and tested them on lab mice through the observation of the variations in bleeding time(BT), clotting time(CT), platelet, red blood cells(RBC), packed cell volume(PCV), white blood cells (WBC) and hemoglobin counts(Hb) with Calcium count (Ca) in blood. The results revealed differences in the percentage of alkaloids in the plants under the study; Zingiber was the higher one followed by Thymus and Acacia respectively.Zingiberwas also the most effective plant as coagulant factor than other two plants as it decreased both BT and CT and increased platelets, RBC, PCV, WBC and Ca count. more than what T. vulgaris and A. arabica affected on blood characters mentioned before. http://pubs.sciepub.com/bb/1/2/3/bb-1-2-3.pdf alkaloidscoagulant agentbleeding timeclotting timeplateletsblood cellspacked cell volumewhite blood cellshemoglobin and calcium counts