@article{ajps2020821,
author={{Ajeet, A and Aggarwal, Babita and Verma, Santosh Kumar and Singh, Ajeet},
title={Docking Analysis of 07 Anti-HCV Drugs with COVID-19 Main Protease PDB ID: 6LU7},
journal={American Journal of Pharmacological Sciences},
volume={8},
number={2},
pages={21--25},
year={2020},
url={http://pubs.sciepub.com/ajps/8/2/1},
issn={2327-672X},
abstract={07 anti-HCV drugs have been processed and observed by docking analysis for understanding the binding patteren of drugs with COVID-19 main protease PDB ID: 6LU7 for any possibilities of protease inhibition. For docking analysis PyRx- Python Prescription 0.8 was used. This analysis reveals that the essential amino acids involved in binding of anti-HCV drugs to COVID-19 main protease PDB ID: 6LU7 are Threonine (THR), Cysteine (CYS), Histidine (HIS), Methionine (MET) and Proline (PRO). After docking analysis it was observed that Ledipasvir may be act as COVID-19 main protease inhibitor despite of being anti-HCV and may further be used in the treatment of COVID-19 infection after having proper clinical proofs.},
doi={10.12691/ajps-8-2-1}
publisher={Science and Education Publishing}
}