eng Science and Education Publishing American Journal of Pharmacological Sciences 2327-672X 2020-04-13 8 1 7 8 10.12691/ajps-8-1-2 AJPS2020812 article A Ajeet ajeet_pharma111@rediffmail.com 1 Babita Aggarwal 2 Santosh Kumar Verma 2 Faculty of Pharmaceutical Sciences, Motherhood University, Roorkee, India School of Pharmacy, Vishveshwarya Group of Institutions, G. Noida, India The aim of this review is to understanding and finding the mode of a synthetic chemical molecule or peptide that could crack outbreak of human corona virus nCoV-19 (COVID-19) to some extent or you can say that selecting the best from what has been already tried. To fulfill this aim we started searching research / review article database of PUBMED. After comparing possible options of combating the problem, peptide intervention and synthetic moieties have been found that could break the outbreak of COVID-19. http://pubs.sciepub.com/ajps/8/1/2/ajps-8-1-2.pdf corona virus Covid-19 protease ACE-2 pyrazolones