Science and Education Publishing American Journal of Pharmacological Sciences 2 1 2014 02 07 Membrane Stability of Red Blood Cells in Diabetic Mice Treated with D-3-O-Methylchiroinositol 24 26 EN Nwaehujor Chinaka O Department of Biochemistry, Faculty of Basic Medical, Sciences, University of Calabar, P.M.B. 1115, Calabar, Nigeria Asuzu Onyeka V Asuzu Isaac U AJPS2014215 10.12691/ajps-2-1-5 2014 01 17 2014 01 24 2014 02 07 D-3-O-methylchiroinositol isolated from the stem bark of Piliostigma thonningii was evaluated for membrane stabilizing potentials in red blood cells of alloxan-induced diabetic albino Swiss mice. Blood from diabetic animals treated with different doses of the compound (8, 4, 2 mg/kg) and Glibenclamide (2 mg/kg) were measured for membrane stability at different saline concentrations. The MCF values and their corresponding percentage stabilization were increased in the treatment groups compared to the negative control. The result suggests that D-3-O-methylchiroinositol possesses membrane stabilizing potentials.