eng Science and Education Publishing American Journal of Public Health Research 2327-6703 2019-07-29 7 4 157 160 10.12691/ajphr-7-4-5 AJPHR2019745 article Emad M. Mukhtar Alasar 1 Mohammed A. Ali Omer alkajam@gmail.com 2 3 Ghada A. E. Sakin 3 Department of Radiotherapy & Nuclear Medicine, College of Medical Radiologic Science, Sudan University of Science and Technology, Khartoum-Sudan Department of Radiology, College of Applied Medical Science, King Khalid University, Abha-KSA A retrospective study aims to assess aging impact in cranial/ventricles volumes and the effect in signal intensity of imaging modalities (CT & MRI). The analysis of collected data using Excel and SPSS showed that: aging has less significant (R2 =0.4) impact on ventricle volume generally and the correlation best fitted to equation: Volume = 1.46 age - 40.742. The impact of aging in ventricles volume was significant (p = 0.05) increment after 69 years with prominent effect among male relative to female; and steady before the age of 69 years old. Aging had less significant decreasing impact (R2 = 0.3) in signal intensity (T1, T2) of white and gray matter and having prominent high signal intensity of white mater relative to gray mater. The age showed high significant (R2 = 0.8) reducing impact in white matter HU that fitted to equations of the following forms: HU = 0.53 age + 9.6864; while there is an increasing impact in gray matter HU that fitted to: HU = -0.26 age + 40.093. http://pubs.sciepub.com/ajphr/7/4/5/ajphr-7-4-5.pdf volumetric cranium ventricle ageing-impact